Flavonoid modulation of GABA(A) receptors

Por Hanrahan, Jane R, Chebib, Mary, Johnston, Graham A R
Publicado em 2011

The Direct Actions of GABA, 2’-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABA(A) Receptors: Evidence for Receptors with Different Subunit Stoichiometries

Por Chua, Han Chow, Absalom, Nathan L., Hanrahan, Jane R., Viswas, Raja, Chebib, Mary
Publicado no PLoS One (2015)

Structure of the PLP-Form of the Human Kynurenine Aminotransferase II in a Novel Spacegroup at 1.83 Å Resolution

Por Nematollahi, Alireza, Sun, Guanchen, Harrop, Stephen J., Hanrahan, Jane R., Church, W. Bret
Publicado no Int J Mol Sci (2016)

GABA‐ρ receptors: distinctive functions and molecular pharmacology

Por Naffaa, Moawiah M, Hung, Sandy, Chebib, Mary, Johnston, Graham A R, Hanrahan, Jane R
Publicado no Br J Pharmacol (2017)

Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q

Por Yow, Tin T, Pera, Elena, Absalom, Nathan, Heblinski, Marika, Johnston, Graham AR, Hanrahan, Jane R, Chebib, Mary
Publicado em 2011

Flavan-3-ol esters: new agents for exploring modulatory sites on GABA(A) receptors

Por Fernandez, Sebastian P, Karim, Nasiara, Mewett, Kenneth N, Chebib, Mary, Johnston, Graham AR, Hanrahan, Jane R
Publicado em 2012

Investigating the Role of Loop C Hydrophilic Residue ‘T244’ in the Binding Site of ρ1 GABA(C) Receptors via Site Mutation and Partial Agonism

Por Naffaa, Moawiah M., Absalom, Nathan, Solomon, V. Raja, Chebib, Mary, Hibbs, David E., Hanrahan, Jane R.
Publicado no PLoS One (2016)

2′-Methoxy-6-methylflavone: a novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptors

Por Karim, Nasiara, Curmi, John, Gavande, Navnath, Johnston, Graham AR, Hanrahan, Jane R, Tierney, M Louise, Chebib, Mary
Publicado em 2012

Design, Synthesis, and Pharmacological Evaluation of Fluorescent and Biotinylated Antagonists of ρ(1) GABA(C) Receptors

Por Gavande, Navnath, Kim, Hye-Lim, Doddareddy, Munikumar R., Johnston, Graham A. R., Chebib, Mary, Hanrahan, Jane R.
Publicado em 2013

Differentiating Enantioselective Actions of GABOB: A Possible Role for Threonine 244 in the Binding Site of GABA(C) ρ(1) Receptors

Por Yamamoto, Izumi, Absalom, Nathan, Carland, Jane E., Doddareddy, Munikumar R., Gavande, Navnath, Johnston, Graham A. R., Hanrahan, Jane R., Chebib, Mary
Publicado em 2012

Spontaneous Adverse Event Reports Associated with Zolpidem in the United States 2003–2012

Por Wong, Carmen K., Marshall, Nathaniel S., Grunstein, Ronald R., Ho, Samuel S., Fois, Romano A., Hibbs, David E., Hanrahan, Jane R., Saini, Bandana
Publicado no J Clin Sleep Med (2017)

Novel Cyclic Phosphinic Acids as GABA(C) ρ Receptor Antagonists: Design, Synthesis, and Pharmacology

Por Gavande, Navnath, Yamamoto, Izumi, Salam, Noeris K., Ai, Tu-Hoa, Burden, Peter M., Johnston, Graham A. R., Hanrahan, Jane R., Chebib, Mary
Publicado em 2010

Structurally Diverse GABA Antagonists Interact Differently with Open and Closed Conformational States of the ρ(1) Receptor

Por Yamamoto, Izumi, Carland, Jane E., Locock, Katherine, Gavande, Navnath, Absalom, Nathan, Hanrahan, Jane R., Allan, Robin D., Johnston, Graham A. R., Chebib, Mary
Publicado em 2012

Novel, Potent, and Selective GABA(C) Antagonists Inhibit Myopia Development and Facilitate Learning and Memory

Por Chebib, Mary, Hinton, Tina, Schmid, Katrina L., Brinkworth, Darren, Qian, Haohua, Matos, Susana, Kim, Hye-Lim, Abdel-Halim, Heba, Kumar, Rohan J., Johnston, Graham A. R., Hanrahan, Jane R.
Publicado em 2009

GABA(A) Receptors Containing ρ1 Subunits Contribute to In Vivo Effects of Ethanol in Mice

Por Blednov, Yuri A., Benavidez, Jillian M., Black, Mendy, Leiter, Courtney R., Osterndorff-Kahanek, Elizabeth, Johnson, David, Borghese, Cecilia M., Hanrahan, Jane R., Johnston, Graham A. R., Chebib, Mary, Harris, R. Adron
Publicado em 2014