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The Direct Actions of GABA, 2’-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABA(A) Receptors: Evidence for Receptors with Different Subunit Stoichiometries
2’-Methoxy-6-methylflavone (2’MeO6MF) is an anxiolytic flavonoid which has been shown to display GABA(A) receptor (GABA(A)R) β2/3-subunit selectivity, a pharmacological profile similar to that of the general anaesthetic etomidate. Electrophysiological studies suggest that the full agonist action of...
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| Yayımlandı: | PLoS One |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4619705/ https://ncbi.nlm.nih.gov/pubmed/26496640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141359 |
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