The Direct Actions of GABA, 2’-Methoxy-6-Methylflavone and General Anaesthetics at β3γ2L GABA(A) Receptors: Evidence for Receptors with Different Subunit Stoichiometries

2’-Methoxy-6-methylflavone (2’MeO6MF) is an anxiolytic flavonoid which has been shown to display GABA(A) receptor (GABA(A)R) β2/3-subunit selectivity, a pharmacological profile similar to that of the general anaesthetic etomidate. Electrophysiological studies suggest that the full agonist action of...

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Veröffentlicht in:PLoS One
Hauptverfasser: Chua, Han Chow, Absalom, Nathan L., Hanrahan, Jane R., Viswas, Raja, Chebib, Mary
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619705/
https://ncbi.nlm.nih.gov/pubmed/26496640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141359
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