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The Z-Drugs Zolpidem, Zaleplon, and Eszopiclone Have Varying Actions on Human GABA(A) Receptors Containing γ1, γ2, and γ3 Subunits

γ-Aminobutyric-acid type A (GABA(A)) receptors expressing the γ1 or γ3 subunit are only found within a few regions of the brain, some of which are involved in sleep. No known compounds have been reported to selectively target γ1- or γ3-containing GABA(A) receptors. Pharmacological assessments of thi...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Richter, Grant, Liao, Vivian W. Y., Ahring, Philip K., Chebib, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710685/
https://ncbi.nlm.nih.gov/pubmed/33328871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.599812
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