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Zolpidem and eszopiclone prime α1β2γ2 GABA(A) receptors for longer duration of activity
BACKGROUND AND PURPOSE: GABA(A) receptors mediate neuronal inhibition in the brain. They are the primary targets for benzodiazepines, which are widely used to treat neurological disorders including anxiety, epilepsy and insomnia. The mechanism by which benzodiazepines enhance GABA(A) receptor activi...
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| Publicado en: | Br J Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507157/ https://ncbi.nlm.nih.gov/pubmed/25817320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13142 |
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