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GABA(A) Receptor α and γ Subunits Shape Synaptic Currents via Different Mechanisms

Synaptic GABA(A) receptors (GABA(A)Rs) mediate most of the inhibitory neurotransmission in the brain. The majority of these receptors are comprised of α1, β2, and γ2 subunits. The amygdala, a structure involved in processing emotional stimuli, expresses α2 and γ1 subunits at high levels. The effect...

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Bibliographic Details
Main Authors: Dixon, Christine, Sah, Pankaj, Lynch, Joseph W., Keramidas, Angelo
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937617/
https://ncbi.nlm.nih.gov/pubmed/24425869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.514695
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