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Novel Cyclic Phosphinic Acids as GABA(C) ρ Receptor Antagonists: Design, Synthesis, and Pharmacology
[Image: see text] Understanding the role of GABA(C) receptors in the central nervous system is limited due to a lack of specific ligands. Novel γ-aminobutyric acid (GABA) analogues based on 3-(aminomethyl)-1-oxo-1-hydroxy-phospholane 17 and 3-(guanido)-1-oxo-1-hydroxy-phospholane 19 were investigate...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical Society
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018128/ https://ncbi.nlm.nih.gov/pubmed/24900248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1001344 |
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