Novel Cyclic Phosphinic Acids as GABA(C) ρ Receptor Antagonists: Design, Synthesis, and Pharmacology

[Image: see text] Understanding the role of GABA(C) receptors in the central nervous system is limited due to a lack of specific ligands. Novel γ-aminobutyric acid (GABA) analogues based on 3-(aminomethyl)-1-oxo-1-hydroxy-phospholane 17 and 3-(guanido)-1-oxo-1-hydroxy-phospholane 19 were investigate...

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Xehetasun bibliografikoak
Egile Nagusiak: Gavande, Navnath, Yamamoto, Izumi, Salam, Noeris K., Ai, Tu-Hoa, Burden, Peter M., Johnston, Graham A. R., Hanrahan, Jane R., Chebib, Mary
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2010
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018128/
https://ncbi.nlm.nih.gov/pubmed/24900248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml1001344
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