Novel, Potent, and Selective GABA(C) Antagonists Inhibit Myopia Development and Facilitate Learning and Memory

This study reports pharmacological and physiological effects of cis- and trans-(3-aminocyclopentanyl)butylphosphinic acid (cis- and trans-3-ACPBPA). These compounds are conformationally restricted analogs of the orally active GABA(B/C) receptor antagonist (3-aminopropyl)-n-butylphosphinic acid (CGP3...

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Detalhes bibliográficos
Main Authors: Chebib, Mary, Hinton, Tina, Schmid, Katrina L., Brinkworth, Darren, Qian, Haohua, Matos, Susana, Kim, Hye-Lim, Abdel-Halim, Heba, Kumar, Rohan J., Johnston, Graham A. R., Hanrahan, Jane R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Neuropharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630368/
https://ncbi.nlm.nih.gov/pubmed/18984654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.146464
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