2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABA(A)-ρ1 Receptors

2-Aminoethyl methylphosphonate (2-AEMP), an analog of GABA, has been found to exhibit antagonist activity at GABA(A)-ρ1 (also known as ρ1 GABA(C)) receptors. The present study was undertaken to elucidate 2-AEMP's action and to test the activities of 2-AEMP analogs. Whole-cell patch-clamp techni...

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Detalhes bibliográficos
Main Authors: Xie, An, Yan, Jun, Yue, Lan, Feng, Feng, Mir, Fozia, Abdel-Halim, Heba, Chebib, Mary, Le Breton, Guy C., Standaert, Robert F., Qian, Haohua, Pepperberg, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228531/
https://ncbi.nlm.nih.gov/pubmed/21810922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.071225
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