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DNA repair targeted therapy: the past or future of cancer treatment?

The repair of DNA damage is a complex process that relies on particular pathways to remedy specific types of damage to DNA. The range of insults to DNA includes small, modest changes in structure including mismatched bases and simple methylation events to oxidized bases, intra- and interstrand DNA c...

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Detalles Bibliográficos
Publicado en:Pharmacol Ther
Main Authors: Gavande, Navnath S., VanderVere-Carozza, Pamela S., Hinshaw, Hilary D., Jalal, Shadia I., Sears, Catherine R., Pawelczak, Katherine S., Turchi, John J.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811676/
https://ncbi.nlm.nih.gov/pubmed/26896565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2016.02.003
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