T-type calcium channels regulate cortical plasticity in-vivo

Por Uebele, Victor N., Nuss, Cindy E., Santarelli, Vincent P., Garson, Susan L., Barrow, James C., Stauffer, Shaun R., Koblan, Kenneth S., Renger, John J., Aton, Sara, Seibt, Julie, Dumoulin, Michelle, Jha, Sushil K., Coleman, Tammi, Frank, Marcos G.
Publicado em 2009

Orexin receptor antagonist-induced sleep does not impair the ability to wake in response to emotionally salient acoustic stimuli in dogs

Por Tannenbaum, Pamela L., Stevens, Joanne, Binns, Jacquelyn, Savitz, Alan T., Garson, Susan L., Fox, Steven V., Coleman, Paul, Kuduk, Scott D., Gotter, Anthony L., Marino, Michael, Tye, Spencer J., Uslaner, Jason M., Winrow, Christopher J., Renger, John J.
Publicado em 2014

Differential sleep-promoting effects of dual orexin receptor antagonists and GABA(A) receptor modulators

Por Gotter, Anthony L, Garson, Susan L, Stevens, Joanne, Munden, Regina L, Fox, Steven V, Tannenbaum, Pamela L, Yao, Lihang, Kuduk, Scott D, McDonald, Terrence, Uslaner, Jason M, Tye, Spencer J, Coleman, Paul J, Winrow, Christopher J, Renger, John J
Publicado no BMC Neurosci (2014)

Pharmacological Validation of Candidate Causal Sleep Genes Identified in an N2 Cross

Por Brunner, Joseph I., Gotter, Anthony L., Millstein, Joshua, Garson, Susan, Binns, Jacquelyn, Fox, Steven V., Savitz, Alan T., Yang, He S., Fitzpatrick, Karrie, Zhou, Lili, Owens, Joseph R., Webber, Andrea L., Vitaterna, Martha H., Kasarskis, Andrew, Uebele, Victor N., Turek, Fred, Renger, John J., Winrow, Christopher J.
Publicado em 2011

Antagonism of T-type calcium channels inhibits high-fat diet–induced weight gain in mice

Por Uebele, Victor N., Gotter, Anthony L., Nuss, Cindy E., Kraus, Richard L., Doran, Scott M., Garson, Susan L., Reiss, Duane R., Li, Yuxing, Barrow, James C., Reger, Thomas S., Yang, Zhi-Qiang, Ballard, Jeanine E., Tang, Cuyue, Metzger, Joseph M., Wang, Sheng-Ping, Koblan, Kenneth S., Renger, John J.
Publicado em 2009

Quantitative Electroencephalography Within Sleep/Wake States Differentiates GABA(A) Modulators Eszopiclone and Zolpidem From Dual Orexin Receptor Antagonists in Rats

Por Fox, Steven V, Gotter, Anthony L, Tye, Spencer J, Garson, Susan L, Savitz, Alan T, Uslaner, Jason M, Brunner, Joseph I, Tannenbaum, Pamela L, McDonald, Terrence P, Hodgson, Robert, Yao, Lihang, Bowlby, Mark R, Kuduk, Scott D, Coleman, Paul J, Hargreaves, Richard, Winrow, Christopher J, Renger, John J
Publicado em 2013

Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulator...

Por Ramirez, Andres D., Gotter, Anthony L., Fox, Steven V., Tannenbaum, Pamela L., Yao, Lihang, Tye, Spencer J., McDonald, Terrence, Brunner, Joseph, Garson, Susan L., Reiss, Duane R., Kuduk, Scott D., Coleman, Paul J., Uslaner, Jason M., Hodgson, Robert, Browne, Susan E., Renger, John J., Winrow, Christopher J.
Publicado em 2013

Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to Man

Por Gotter, Anthony L., Forman, Mark S., Harrell, Charles M., Stevens, Joanne, Svetnik, Vladimir, Yee, Ka Lai, Li, Xiaodong, Roecker, Anthony J., Fox, Steven V., Tannenbaum, Pamela L., Garson, Susan L., Lepeleire, Inge De, Calder, Nicole, Rosen, Laura, Struyk, Arie, Coleman, Paul J., Herring, W. Joseph, Renger, John J., Winrow, Christopher J.
Publicado no Sci Rep (2016)

The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold

Por Gotter, Anthony L, Winrow, Christopher J, Brunner, Joseph, Garson, Susan L, Fox, Steven V, Binns, Jacquelyn, Harrell, Charles M, Cui, Donghui, Yee, Ka Lai, Stiteler, Mark, Stevens, Joanne, Savitz, Alan, Tannenbaum, Pamela L, Tye, Spencer J, McDonald, Terrence, Yao, Leon, Kuduk, Scott D, Uslaner, Jason, Coleman, Paul J, Renger, John J
Publicado em 2013

Selective activation of the M(1) muscarinic acetylcholine receptor achieved by allosteric potentiation

Por Ma, Lei, Seager, Matthew A., Wittmann, Marion, Jacobson, Marlene, Bickel, Denise, Burno, Maryann, Jones, Keith, Graufelds, Valerie Kuzmick, Xu, Guangping, Pearson, Michelle, McCampbell, Alexander, Gaspar, Renee, Shughrue, Paul, Danziger, Andrew, Regan, Christopher, Flick, Rose, Pascarella, Danette, Garson, Susan, Doran, Scott, Kreatsoulas, Constantine, Veng, Lone, Lindsley, Craig W., Shipe, William, Kuduk, Scott, Sur, Cyrille, Kinney, Gene, Seabrook, Guy R., Ray, William J.
Publicado em 2009

Discovery of 4,4-Disubstituted Quinazolin-2-ones as T-Type Calcium Channel Antagonists

Por Barrow, James C., Rittle, Kenneth E., Reger, Thomas S., Yang, Zhi-Qiang, Bondiskey, Phung, McGaughey, Georgia B., Bock, Mark G., Hartman, George D., Tang, Cuyue, Ballard, Jeanine, Kuo, Yuhsin, Prueksaritanont, Thomayant, Nuss, Cindy E., Doran, Scott M., Fox, Steven V., Garson, Susan L., Kraus, Richard L., Li, Yuxing, Marino, Michael J., Kuzmick Graufelds, Valerie, Uebele, Victor N., Renger, John J.
Publicado em 2010

Short-Acting T-Type Calcium Channel Antagonists Significantly Modify Sleep Architecture in Rodents

Por Yang, Zhi-Qiang, Schlegel, Kelly-Ann S., Shu, Youheng, Reger, Thomas S., Cube, Rowena, Mattern, Christa, Coleman, Paul J., Small, Jim, Hartman, George D., Ballard, Jeanine, Tang, Cuyue, Kuo, Yuhsin, Prueksaritanont, Thomayant, Nuss, Cindy E., Doran, Scott, Fox, Steve V., Garson, Susan L., Li, Yuxing, Kraus, Richard L., Uebele, Victor N., Taylor, Adekemi B., Zeng, Wei, Fang, Wei, Chavez-Eng, Cynthia, Troyer, Matthew D., Luk, Julie Ann, Laethem, Tine, Cook, William O., Renger, John J., Barrow, James C.
Publicado em 2010