Short-Acting T-Type Calcium Channel Antagonists Significantly Modify Sleep Architecture in Rodents

[Image: see text] A novel phenyl acetamide series of short-acting T-type calcium channel antagonists has been identified and evaluated using in vitro and in vivo assays. Heterocycle substitutions of the 4-position of the phenyl acetamides afforded potent and selective antagonists that exhibited desi...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Yang, Zhi-Qiang, Schlegel, Kelly-Ann S., Shu, Youheng, Reger, Thomas S., Cube, Rowena, Mattern, Christa, Coleman, Paul J., Small, Jim, Hartman, George D., Ballard, Jeanine, Tang, Cuyue, Kuo, Yuhsin, Prueksaritanont, Thomayant, Nuss, Cindy E., Doran, Scott, Fox, Steve V., Garson, Susan L., Li, Yuxing, Kraus, Richard L., Uebele, Victor N., Taylor, Adekemi B., Zeng, Wei, Fang, Wei, Chavez-Eng, Cynthia, Troyer, Matthew D., Luk, Julie Ann, Laethem, Tine, Cook, William O., Renger, John J., Barrow, James C.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2010
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007914/
https://ncbi.nlm.nih.gov/pubmed/24900239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100170e
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares