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Pharmacokinetic de-risking tools for selection of monoclonal antibody lead candidates

Pharmacokinetic studies play an important role in all stages of drug discovery and development. Recent advancements in the tools for discovery and optimization of therapeutic proteins have created an abundance of candidates that may fulfill target product profile criteria. Implementing a set of in s...

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Publicat a:MAbs
Autors principals: Dostalek, Miroslav, Prueksaritanont, Thomayant, Kelley, Robert F.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524161/
https://ncbi.nlm.nih.gov/pubmed/28463063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1323160
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