Loading...
Pharmacokinetics of monoclonal antibodies and Fc-fusion proteins
There are many factors that can influence the pharmacokinetics (PK) of a mAb or Fc-fusion molecule with the primary determinant being FcRn-mediated recycling. Through Fab or Fc engineering, IgG-FcRn interaction can be used to generate a variety of therapeutic antibodies with significantly enhanced h...
Na minha lista:
| Udgivet i: | Protein Cell |
|---|---|
| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Higher Education Press
2017
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5777971/ https://ncbi.nlm.nih.gov/pubmed/28421387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0408-4 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|