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ADME of Biologics—What Have We Learned from Small Molecules?

Thorough characterization and in-depth understanding of absorption, distribution, metabolism, and elimination (ADME) properties of a drug candidate have been well recognized as an important element in small molecule (SM) drug discovery and development. This has been the area of focus for drug metabo...

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Autori principali: Prueksaritanont, Thomayant, Tang, Cuyue
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385832/
https://ncbi.nlm.nih.gov/pubmed/22484625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9353-6
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