Differential sleep-promoting effects of dual orexin receptor antagonists and GABA(A) receptor modulators

BACKGROUND: The current standard of care for insomnia includes gamma-aminobutyric acid receptor A (GABA(A)) activators, which promote sleep as well as general central nervous system depression. Dual orexin receptor antagonists (DORAs) represent an alternative mechanism for insomnia treatment that in...

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Vydáno v:BMC Neurosci
Hlavní autoři: Gotter, Anthony L, Garson, Susan L, Stevens, Joanne, Munden, Regina L, Fox, Steven V, Tannenbaum, Pamela L, Yao, Lihang, Kuduk, Scott D, McDonald, Terrence, Uslaner, Jason M, Tye, Spencer J, Coleman, Paul J, Winrow, Christopher J, Renger, John J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261741/
https://ncbi.nlm.nih.gov/pubmed/25242351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-109
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