Differential sleep-promoting effects of dual orexin receptor antagonists and GABA(A) receptor modulators

BACKGROUND: The current standard of care for insomnia includes gamma-aminobutyric acid receptor A (GABA(A)) activators, which promote sleep as well as general central nervous system depression. Dual orexin receptor antagonists (DORAs) represent an alternative mechanism for insomnia treatment that in...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Gotter, Anthony L, Garson, Susan L, Stevens, Joanne, Munden, Regina L, Fox, Steven V, Tannenbaum, Pamela L, Yao, Lihang, Kuduk, Scott D, McDonald, Terrence, Uslaner, Jason M, Tye, Spencer J, Coleman, Paul J, Winrow, Christopher J, Renger, John J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261741/
https://ncbi.nlm.nih.gov/pubmed/25242351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-109
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