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Differential sleep-promoting effects of dual orexin receptor antagonists and GABA(A) receptor modulators

BACKGROUND: The current standard of care for insomnia includes gamma-aminobutyric acid receptor A (GABA(A)) activators, which promote sleep as well as general central nervous system depression. Dual orexin receptor antagonists (DORAs) represent an alternative mechanism for insomnia treatment that in...

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Bibliografische gegevens
Gepubliceerd in:BMC Neurosci
Hoofdauteurs: Gotter, Anthony L, Garson, Susan L, Stevens, Joanne, Munden, Regina L, Fox, Steven V, Tannenbaum, Pamela L, Yao, Lihang, Kuduk, Scott D, McDonald, Terrence, Uslaner, Jason M, Tye, Spencer J, Coleman, Paul J, Winrow, Christopher J, Renger, John J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261741/
https://ncbi.nlm.nih.gov/pubmed/25242351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-109
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