Inhibition of Orexin Signaling Promotes Sleep Yet Preserves Salient Arousability in Monkeys

STUDY OBJECTIVES: In addition to enhancing sleep onset and maintenance, a desirable insomnia therapeutic agent would preserve healthy sleep's ability to wake and respond to salient situations while maintaining sleep during irrelevant noise. Dual orexin receptor antagonists (DORAs) promote sleep...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sleep
Päätekijät: Tannenbaum, Pamela L., Tye, Spencer J., Stevens, Joanne, Gotter, Anthony L., Fox, Steven V., Savitz, Alan T., Coleman, Paul J., Uslaner, Jason M., Kuduk, Scott D., Hargreaves, Richard, Winrow, Christopher J., Renger, John J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Associated Professional Sleep Societies, LLC 2016
Aiheet:
Basic Science
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763356/
https://ncbi.nlm.nih.gov/pubmed/26943466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.5536
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