Pharmacological characterization of guanidinoethyldisulphide (GED), a novel inhibitor of nitric oxide synthase with selectivity towards the inducible isoform.

Por Szabó, C., Bryk, R., Zingarelli, B., Southan, G. J., Gahman, T. C., Bhat, V., Salzman, A. L., Wolff, D. J.
Publicado em 1996

Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation

Por Carthy, Jon M., Stöter, Martin, Bellomo, Claudia, Vanlandewijck, Michael, Heldin, Angelos, Morén, Anita, Kardassis, Dimitris, Gahman, Timothy C., Shiau, Andrew K., Bickle, Marc, Zerial, Marino, Heldin, Carl-Henrik, Moustakas, Aristidis
Publicado no Sci Rep (2016)

Inhibition of Inducible Nitric Oxide Synthase Expression by a Novel Small Molecule Activator of the Unfolded Protein Response

Por Symons, Kent T, Massari, Mark E, Dozier, Sara J, Nguyen, Phan M, Jenkins, David, Herbert, Mark, Gahman, Timothy C, Noble, Stewart A, Rozenkrants, Natasha, Zhang, Yan, Rao, Tadimeti S, Shiau, Andrew K, Hassig, Christian A
Publicado em 2008

A Cell Biologist’s Field Guide to Aurora Kinase Inhibitors

Por de Groot, Christian O., Hsia, Judy E., Anzola, John V., Motamedi, Amir, Yoon, Michelle, Wong, Yao Liang, Jenkins, David, Lee, Hyun J., Martinez, Mallory B., Davis, Robert L., Gahman, Timothy C., Desai, Arshad, Shiau, Andrew K.
Publicado no Front Oncol (2015)

Reversible centriole depletion with an inhibitor of Polo-like kinase 4

Por Wong, Yao Liang, Anzola, John V., Davis, Robert L., Yoon, Michelle, Motamedi, Amir, Kroll, Ashley, Seo, Chanmee P., Hsia, Judy E., Kim, Sun K., Mitchell, Jennifer W., Mitchell, Brian J., Desai, Arshad, Gahman, Timothy C., Shiau, Andrew K., Oegema, Karen
Publicado no Science (2015)

mTORC2 regulates amino acid metabolism in cancer by phosphorylation of the cystine-glutamate antiporter xCT

Por Gu, Yuchao, Albuquerque, Claudio P., Braas, Daniel, Zhang, Wei, Villa, Genaro R., Bi, Junfeng, Ikegami, Shiro, Masui, Kenta, Gini, Beatrice, Yang, Huijun, Gahman, Timothy C., Shiau, Andrew K., Cloughesy, Timothy F., Christofk, Heather R., Zhou, Huilin, Guan, Kun-Liang, Mischel, Paul S.
Publicado no Mol Cell (2017)

An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons

Por Boselli, Monica, Lee, Byung-Hoon, Robert, Jessica, Prado, Miguel A., Min, Sang-Won, Cheng, Chialin, Silva, M. Catarina, Seong, Changhyun, Elsasser, Suzanne, Hatle, Ketki M., Gahman, Timothy C., Gygi, Steven P., Haggarty, Stephen J., Gan, Li, King, Randall W., Finley, Daniel
Publicado no J Biol Chem (2017)

EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling

Por Liu, Feng, Hon, Gary C., Villa, Genaro R., Turner, Kristen M., Ikegami, Shiro, Yang, Huijun, Ye, Zhen, Li, Bin, Kuan, Samantha, Lee, Ah Young, Zanca, Ciro, Wei, Bowen, Lucey, Greg, Jenkins, David, Zhang, Wei, Barr, Cathy L., Furnari, Frank B., Cloughesy, Timothy F., Yong, William H., Gahman, Timothy C., Shiau, Andrew K., Cavenee, Webster K., Ren, Bing, Mischel, Paul S.
Publicado no Mol Cell (2015)

An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers

Por Villa, Genaro R., Hulce, Jonathan J., Zanca, Ciro, Bi, Junfeng, Ikegami, Shiro, Cahill, Gabrielle L., Gu, Yuchao, Lum, Kenneth M., Masui, Kenta, Yang, Huijun, Rong, Xin, Hong, Cynthia, Turner, Kristen M., Liu, Feng, Hon, Gary C., Jenkins, David, Martini, Michael, Armando, Aaron M., Quehenberger, Oswald, Cloughesy, Timothy F., Furnari, Frank B., Cavenee, Webster K., Tontonoz, Peter, Gahman, Timothy C., Shiau, Andrew K., Cravatt, Benjamin F., Mischel, Paul S.
Publicado no Cancer Cell (2016)

Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity

Por Zanca, Ciro, Villa, Genaro R., Benitez, Jorge A., Thorne, Amy Haseley, Koga, Tomoyuki, D'Antonio, Matteo, Ikegami, Shiro, Ma, Jianhui, Boyer, Antonia D., Banisadr, Afsheen, Jameson, Nathan M., Parisian, Alison D., Eliseeva, Olesja V., Barnabe, Gabriela F., Liu, Feng, Wu, Sihan, Yang, Huijun, Wykosky, Jill, Frazer, Kelly A., Verkhusha, Vladislav V., Isaguliants, Maria G., Weiss, William A., Gahman, Timothy C., Shiau, Andrew K., Chen, Clark C., Mischel, Paul S., Cavenee, Webster K., Furnari, Frank B.
Publicado no Genes Dev (2017)