CYP3A5 Genotype Impacts Maraviroc Concentrations in Healthy Volunteers

Por Lu, Yanhui, Fuchs, Edward J., Hendrix, Craig W., Bumpus, Namandjé N.
Publicado em 2014

Response to “Clinical Relevance of CYP3A5 Genotype on Maraviroc Exposures”

Por Lu, Yanhui, Fuchs, Edward J., Hendrix, Craig W., Bumpus, Namandjé N.
Publicado no Drug Metab Dispos (2015)

When a Serious Adverse Event in Research Occurs, How Do Other Volunteers React?

Por Kennedy, Caitlin E., Kass, Nancy, Myers, Rachel K., Fuchs, Edward J., Flexner, Charles
Publicado em 2011

A Pilot Study Measuring the Distribution and Permeability of a Vaginal HIV Microbicide Gel Vehicle Using Magnetic Resonance Imaging, Single Photon Emission Computed Tomography/Comp...

Por Fuchs, Edward J., Schwartz, Jill L., Friend, David R., Coleman, Jenell S., Hendrix, Craig W.
Publicado no AIDS Res Hum Retroviruses (2015)

Quantitative Assessment of Altered Rectal Mucosal Permeability Due to Rectally Applied Nonoxynol-9, Biopsy, and Simulated Intercourse

Por Fuchs, Edward J., Grohskopf, Lisa A., Lee, Linda A., Bakshi, Rahul P., Hendrix, Craig W.
Publicado em 2013

Biphasic Elimination of Tenofovir Diphosphate and Nonlinear Pharmacokinetics of Zidovudine Triphosphate in a Microdosing Study

Por Chen, Jianmeng, Flexner, Charles, Liberman, Rosa G., Skipper, Paul L., Louissaint, Nicolette, Tannenbaum, Steven R., Hendrix, Craig, Fuchs, Edward
Publicado em 2012

Pharmacokinetics and Safety of AMD-3100, a Novel Antagonist of the CXCR-4 Chemokine Receptor, in Human Volunteers

Por Hendrix, Craig W., Flexner, Charles, MacFarland, Ronald T., Giandomenico, Christen, Fuchs, Edward J., Redpath, Ella, Bridger, Gary, Henson, Geoffrey W.
Publicado em 2000

Plasma and intracellular ribavirin concentrations are not significantly altered by abacavir in hepatitis C virus-infected patients

Por Fuchs, Edward J., Kiser, Jennifer J., Hendrix, Craig W., Sulkowski, Mark, Radebaugh, Christine, Bushman, Lane, Ray, Michelle L., Andrade, Adriana
Publicado no J Antimicrob Chemother (2016)

FEASIBILITY OF RADIOLABELED SMALL MOLECULE PERMEABILITY AS A QUANTITATIVE MEASURE OF MICROBICIDE CANDIDATE TOXICITY

Por Coleman, Jenell, Fuchs, Edward, Aung, Wutyi S., Marzinke, Mark A., Bakshi, Rahul P., Spiegel, Hans M.L., Robinson, Jennifer, Hendrix, Craig W.
Publicado no Contraception (2016)

Phase 1 Clinical Trials of DAS181, an Inhaled Sialidase, in Healthy Adults

Por Zenilman, Jonathan M., Fuchs, Edward J., Hendrix, Craig W., Radebaugh, Christine, Jurao, Robert, Nayak, Seema U., Hamilton, Robert G., Griffiss, J. McLeod
Publicado no Antiviral Res (2015)

The slippery slope: Lubricant Use and Rectal Sexually Transmitted Infections: a newly identified risk

Por Gorbach, Pamina M., Weiss, Robert E., Fuchs, Edward, Jeffries, Robin A., Hezerah, Marjan, Brown, Stephen, Voskanian, Alen, Robbie, Edward, Anton, Peter, Cranston, Ross D.
Publicado em 2012

Order of Orifices: Sequence of Condom Use and Ejaculation by Orifice during Anal Intercourse among Women, Implications for HIV Transmission

Por Gorbach, Pamina M., Pines, Heather, Javanbakht, Marjan, Weiss, Robert E., Jeffries, Robin, Cranston, Ross D., Fuchs, Edward J, Hezerah, Marjan, Brown, Stephen, Voskanian, Alen, Anton, Peter
Publicado em 2014

Comparison of Dapivirine Vaginal Gel and Film Formulation Pharmacokinetics and Pharmacodynamics (FAME 02B)

Por Robinson, Jennifer A., Marzinke, Mark A., Bakshi, Rahul P., Fuchs, Edward J., Radebaugh, Christine L., Aung, Wutyi, Spiegel, Hans M.L., Coleman, Jenell S., Rohan, Lisa C., Hendrix, Craig W.
Publicado no AIDS Res Hum Retroviruses (2017)

Single Dose Pharmacokinetics of Oral Tenofovir in Plasma, Peripheral Blood Mononuclear Cells, Colonic Tissue, and Vaginal Tissue

Por Louissaint, Nicolette A., Cao, Ying-Jun, Skipper, Paul L., Liberman, Rosa G., Tannenbaum, Steven R., Nimmagadda, Sridhar, Anderson, Jean R., Everts, Stephanie, Bakshi, Rahul, Fuchs, Edward J., Hendrix, Craig W.
Publicado em 2013

Quantification of the spatial distribution of rectally applied surrogates for microbicide and semen in colon with SPECT and magnetic resonance imaging

Por Cao, Ying J, Caffo, Brian S, Fuchs, Edward J, Lee, Linda A, Du, Yong, Li, Liye, Bakshi, Rahul P, Macura, Katarzyna, Khan, Wasif A, Wahl, Richard L, Grohskopf, Lisa A, Hendrix, Craig W
Publicado em 2012

Distribution of Cell-free and Cell-associated HIV surrogates in the Colon Following Simulated Receptive Anal Intercourse in Men who Have Sex with Men

Por LOUISSAINT, Nicolette A., NIMMAGADDA, Sridhar, FUCHS, Edward J., BAKSHI, Rahul P., CAO, Ying, LEE, Linda A., GOLDSMITH, Jeff, CAFFO, Brian S., DU, Yong, KING, Karen E., MENENDEZ, Frederick A., TORBENSON, Michael S., HENDRIX, Craig W.
Publicado em 2012

Isoosmolar Enemas Demonstrate Preferential Gastrointestinal Distribution, Safety, and Acceptability Compared with Hyperosmolar and Hypoosmolar Enemas as a Potential Delivery Vehicl...

Por Leyva, Francisco J., Bakshi, Rahul P., Fuchs, Edward J., Li, Liye, Caffo, Brian S., Goldsmith, Arthur J., Ventuneac, Ana, Carballo-Diéguez, Alex, Du, Yong, Leal, Jeffrey P., Lee, Linda A., Torbenson, Michael S., Hendrix, Craig W.
Publicado em 2013

Simultaneous Evaluation of Safety, Acceptability, Pericoital Kinetics, and Ex Vivo Pharmacodynamics Comparing Four Rectal Microbicide Vehicle Candidates

Por Leyva, Francisco, Fuchs, Edward J., Bakshi, Rahul, Carballo-Dieguez, Alex, Ventuneac, Ana, Yue, Chen, Caffo, Brian, Du, Yong, Torbenson, Michael, Li, Liye, Mullin, Gerald, Lee, Linda, Rohan, Lisa, Anton, Peter A., Hendrix, Craig W.
Publicado no AIDS Res Hum Retroviruses (2015)

A Phase 1 Randomized, Blinded Comparison of the Pharmacokinetics and Colonic Distribution of Three Candidate Rectal Microbicide Formulations of Tenofovir 1% Gel with Simulated Unpr...

Por Hiruy, Hiwot, Fuchs, Edward J., Marzinke, Mark A., Bakshi, Rahul P., Breakey, Jennifer C., Aung, Wutyi S., Manohar, Madhuri, Yue, Chen, Caffo, Brian S., Du, Yong, Abebe, Kaleab Z., Spiegel, Hans M.L., Rohan, Lisa C., McGowan, Ian, Hendrix, Craig W.
Publicado no AIDS Res Hum Retroviruses (2015)

Dose Frequency Ranging Pharmacokinetic Study of Tenofovir-Emtricitabine After Directly Observed Dosing in Healthy Volunteers to Establish Adherence Benchmarks (HPTN 066)

Por Hendrix, Craig W., Andrade, Adriana, Bumpus, Namandjé N., Kashuba, Angela D., Marzinke, Mark A., Moore, Ayana, Anderson, Peter L., Bushman, Lane R., Fuchs, Edward J., Wiggins, Ilene, Radebaugh, Christine, Prince, Heather A., Bakshi, Rahul P., Wang, Ruili, Richardson, Paul, Shieh, Eugenie, McKinstry, Laura, Li, Xin, Donnell, Deborah, Elharrar, Vanessa, Mayer, Kenneth H., Patterson, Kristine B.
Publicado no AIDS Res Hum Retroviruses (2016)