Quantitative Assessment of Altered Rectal Mucosal Permeability Due to Rectally Applied Nonoxynol-9, Biopsy, and Simulated Intercourse

Background. Microbicide toxicity may reduce the efficacy of topical preexposure prophylaxis for human immunodeficiency virus (HIV) transmission. Noninvasive quantitative measures of microbicide toxicity would usefully inform microbicide development. Methods. Ten subjects received 3 one-time interven...

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Detalhes bibliográficos
Main Authors: Fuchs, Edward J., Grohskopf, Lisa A., Lee, Linda A., Bakshi, Rahul P., Hendrix, Craig W.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693591/
https://ncbi.nlm.nih.gov/pubmed/23325915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit030
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