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Quantitative Assessment of Altered Rectal Mucosal Permeability Due to Rectally Applied Nonoxynol-9, Biopsy, and Simulated Intercourse

Background. Microbicide toxicity may reduce the efficacy of topical preexposure prophylaxis for human immunodeficiency virus (HIV) transmission. Noninvasive quantitative measures of microbicide toxicity would usefully inform microbicide development. Methods. Ten subjects received 3 one-time interven...

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Bibliografiske detaljer
Main Authors: Fuchs, Edward J., Grohskopf, Lisa A., Lee, Linda A., Bakshi, Rahul P., Hendrix, Craig W.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693591/
https://ncbi.nlm.nih.gov/pubmed/23325915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit030
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