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Plasma and intracellular ribavirin concentrations are not significantly altered by abacavir in hepatitis C virus-infected patients

OBJECTIVES: The objective of this study was to evaluate the effects of abacavir on intracellular ribavirin triphosphate and plasma ribavirin trough concentrations. METHODS: Hepatitis C virus-infected subjects who had been cured or failed prior treatment were randomized to 8 weeks of ribavirin alone...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Fuchs, Edward J., Kiser, Jennifer J., Hendrix, Craig W., Sulkowski, Mark, Radebaugh, Christine, Bushman, Lane, Ray, Michelle L., Andrade, Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867100/
https://ncbi.nlm.nih.gov/pubmed/26869690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkw009
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