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Measurement of Intracellular Ribavirin Mono-, Di- and Triphosphate Using Solid Phase Extraction and LC-MS/MS Quantification
Ribavirin (RBV) is a nucleoside analog used to treat a variety of DNA and RNA viruses. RBV undergoes intracellular phosphorylation to a mono- (MP), di- (DP), and triphosphate (TP). The phosphorylated forms have been associated with the mechanisms of antiviral effect observed in vitro, but the intrac...
Tallennettuna:
| Julkaisussa: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297558/ https://ncbi.nlm.nih.gov/pubmed/25555148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2014.11.032 |
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