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Validation of a sensitive LC/MS/MS method for the determination of zidovudine and lamivudine in human plasma

A sensitive LC/MS/MS assay for determining zidovudine (ZDV) and lamivudine (3TC) in human plasma was validated to support antiretroviral pharmacology research programs. After addition of stable labeled isotopic zidovudine (ZDV-IS) and lamivudine (3TC-IS) as internal standard, a solid phase extractio...

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Detalhes bibliográficos
Main Authors: Rower, Joseph E., Klein, Brandon, Bushman, Lane R., Anderson, Peter L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188333/
https://ncbi.nlm.nih.gov/pubmed/21465499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.1617
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