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Validation of a LC/MS method for the determination of gemfibrozil in human plasma and its application to a pharmacokinetic study

Gemfibrozil, a fibric acid hypolipidemic agent, is increasingly being used in clinical drug-drug interaction studies as an inhibitor of drug metabolizing enzymes and drug transporters. The validation of a fast, accurate, and precise LC/MS method is described for the quantitative determination of gem...

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Autores principales: Rower, Joseph E., Bushman, Lane R., Hammond, Kyle P., Kadam, Rajendra S., Aquilante, Christina L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071626/
https://ncbi.nlm.nih.gov/pubmed/21077249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.1440
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