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LC-MS/MS determination of etravirine in rat plasma and its application in pharmacokinetic studies

Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that is active against NNRT-resistant HIV-1. A simple, sensitive, and specific LC-MS/MS method was developed and validated for the analysis of etravirine in rat plasma using itraconazole as the internal standard. The analytes wer...

詳細記述

保存先:
書誌詳細
主要な著者: Abobo, Cyril, Wu, Lei, John, Jyothy, Joseph, Mathew K., Bates, Theodore R., Liang, Dong
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008212/
https://ncbi.nlm.nih.gov/pubmed/20965798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.09.016
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