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LC-MS/MS determination of etravirine in rat plasma and its application in pharmacokinetic studies
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that is active against NNRT-resistant HIV-1. A simple, sensitive, and specific LC-MS/MS method was developed and validated for the analysis of etravirine in rat plasma using itraconazole as the internal standard. The analytes wer...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008212/ https://ncbi.nlm.nih.gov/pubmed/20965798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.09.016 |
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