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Rapid and Sensitive Determination of Timosaponin AIII in Rat Plasma by LC-MS/MS and Its Pharmacokinetic Application

A rapid sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for determination of timosaponin AIII (TA-III) in rat plasma, using ginsenoside Re as an internal standard (IS). TA-III and the IS were detected in MRM mode with a negative ionization elect...

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Detalhes bibliográficos
Main Authors: Liu, Yanping, Pu, Yiqiong, Zhang, Tong, Ding, Yue, Wang, Bing, Cai, Zhenzhen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3588063/
https://ncbi.nlm.nih.gov/pubmed/23434663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14023656
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