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Rapid and sensitive LC–MS/MS method for determination of felbamate in mouse plasma and tissues and human plasma

Felbamate (2-phenyl-1,3-propanediol dicarbamate) is a second generation antiepileptic drug used to treat seizures refractory to other antiepileptic drugs. With approximately 3500 new patients exposed annually, several important pharmacologic interaction questions remain unanswered necessitating the...

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Veröffentlicht in:J Chromatogr B Analyt Technol Biomed Life Sci
Hauptverfasser: Hansen, Ryan J., Samber, Bradley J., Gustafson, Daniel L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278804/
https://ncbi.nlm.nih.gov/pubmed/21081288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.10.006
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