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Rapid quantification of vincristine in mouse plasma using ESI-LC-MS/MS: Application to pharmacokinetic studies
A simple, rapid, and sensitive LC-MS/MS method for determining concentrations of the anticancer alkaloid vincristine in micro volumes of mouse plasma was developed and validated in positive ion mode. Separation of vincristine and the internal standard [(2)H(3)]-vincristine was achieved on an Accucor...
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| Publicat a: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7987214/ https://ncbi.nlm.nih.gov/pubmed/33684722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2021.122591 |
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