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CYP3A5 Genotype Impacts Maraviroc Concentrations in Healthy Volunteers
CYP3A5 plays a prominent role in the metabolism of maraviroc, an approved drug for human immunodeficiency virus (HIV)-1 treatment and a candidate for HIV-1 prevention. We studied the effect of the CYP3A5 genotype on pharmacokinetics of maraviroc and a primary CYP3A5-dependent metabolite of maraviroc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201129/ https://ncbi.nlm.nih.gov/pubmed/25117426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.114.060194 |
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