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Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers
AIMS: To evaluate the influence of cytochrome P450 (CYP) 3A4 inhibitors on the clinical pharmacokinetics of maraviroc, a novel CCR5 antagonist. METHODS: Four open-label, randomized, placebo-controlled studies were conducted in healthy subjects to assess the effect of separate and distinct combinatio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2311406/ https://ncbi.nlm.nih.gov/pubmed/18333863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03133.x |
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