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The effects of cotrimoxazole or tenofovir co-administration on the pharmacokinetics of maraviroc in healthy volunteers

AIMS: To assess the potential of cotrimoxazole and tenofovir, drugs which are inhibitors and/or substrates of renal transporters, to alter the pharmacokinetic profile of maraviroc. METHODS: Two randomized, placebo-controlled, two-way crossover studies were conducted in healthy male and female subjec...

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Detalhes bibliográficos
Main Authors: Abel, Samantha, Russell, Deborah, Whitlock, Lyndsey A, Ridgway, Caroline E, Muirhead, Gary J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311416/
https://ncbi.nlm.nih.gov/pubmed/18333865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03135.x
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