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Effect of maraviroc on the pharmacokinetics of midazolam, lamivudine/ zidovudine, and ethinyloestradiol/ levonorgestrel in healthy volunteers

AIMS: To assess the effect of maraviroc on the pharmacokinetics of midazolam, a sensitive probe CYP3A4 substrate; lamivudine/zidovudine, a combination of nucleoside reverse transcriptase inhibitors (NRTIs); and ethinyloestradiol/levonorgestrel, a combination oral contraceptive. METHODS: Three random...

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Bibliografiske detaljer
Main Authors: Abel, Samantha, Russell, Deborah, Whitlock, Lyndsey A, Ridgway, Caroline E, Muirhead, Gary J
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311411/
https://ncbi.nlm.nih.gov/pubmed/18333862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03132.x
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