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Assessment of the absorption, metabolism and absolute bioavailability of maraviroc in healthy male subjects

AIMS: Two studies were conducted to: (i) quantify the amount of drug-related radioactivity in blood, plasma, urine and faeces following a (14)C-labelled dose of maraviroc; and (ii) investigate the pharmacokinetics, safety and tolerability of intravenous (i.v.) maraviroc and determine the absolute bi...

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Detalhes bibliográficos
Main Authors: Abel, Samantha, Russell, Deborah, Whitlock, Lyndsey A, Ridgway, Caroline E, Nedderman, Angus N R, Walker, Donald K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311408/
https://ncbi.nlm.nih.gov/pubmed/18333867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03137.x
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