Assessment of the pharmacokinetics, safety and tolerability of maraviroc, a novel CCR5 antagonist, in healthy volunteers

AIMS: To evaluate the pharmacokinetics, safety and tolerability of single and multiple oral doses of maraviroc in healthy volunteers. METHODS: Three double-blind, placebo-controlled, dose-escalation studies with either single or multiple doses of maraviroc were conducted in healthy volunteers. Plasm...

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Detalhes bibliográficos
Main Authors: Abel, Samantha, van der Ryst, Elna, Rosario, Maria C, Ridgway, Caroline E, Medhurst, Christine G, Taylor-Worth, Richard J, Muirhead, Gary J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2311414/
https://ncbi.nlm.nih.gov/pubmed/18333861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03130.x
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