Dose Frequency Ranging Pharmacokinetic Study of Tenofovir-Emtricitabine After Directly Observed Dosing in Healthy Volunteers to Establish Adherence Benchmarks (HPTN 066)

Oral preexposure prophylaxis (PrEP) trials report disparate efficacy attributed to variable adherence. HPTN 066 was conducted to establish objective, quantitative benchmarks for discrete, regular levels of adherence using directly observed dosing of tenofovir (TFV) disoproxil fumarate (TDF)/emtricit...

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Bibliografske podrobnosti
izdano v:AIDS Res Hum Retroviruses
Main Authors: Hendrix, Craig W., Andrade, Adriana, Bumpus, Namandjé N., Kashuba, Angela D., Marzinke, Mark A., Moore, Ayana, Anderson, Peter L., Bushman, Lane R., Fuchs, Edward J., Wiggins, Ilene, Radebaugh, Christine, Prince, Heather A., Bakshi, Rahul P., Wang, Ruili, Richardson, Paul, Shieh, Eugenie, McKinstry, Laura, Li, Xin, Donnell, Deborah, Elharrar, Vanessa, Mayer, Kenneth H., Patterson, Kristine B.
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2016
Teme:
HIV Prevention
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692123/
https://ncbi.nlm.nih.gov/pubmed/26414912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2015.0182
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