Genetic Variation of the Kinases That Phosphorylate Tenofovir and Emtricitabine in Peripheral Blood Mononuclear Cells

Tenofovir (TFV) disoproxil fumarate and emtricitabine (FTC) are used in combination for HIV treatment and pre-exposure prophylaxis (PrEP). TFV disoproxil fumarate is a prodrug that undergoes diester hydrolysis to TFV. FTC and TFV are nucleoside/nucleotide reverse transcriptase inhibitors that upon p...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:AIDS Res Hum Retroviruses
Hlavní autoři: Figueroa, Dominique B., Madeen, Erin P., Tillotson, Joseph, Richardson, Paul, Cottle, Leslie, McCauley, Marybeth, Landovitz, Raphael J., Andrade, Adriana, Hendrix, Craig W., Mayer, Kenneth H., Wilkin, Timothy, Gulick, Roy M., Bumpus, Namandjé N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934973/
https://ncbi.nlm.nih.gov/pubmed/29455571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2017.0243
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky