Genetic Variation of the Kinases That Phosphorylate Tenofovir and Emtricitabine in Peripheral Blood Mononuclear Cells

Tenofovir (TFV) disoproxil fumarate and emtricitabine (FTC) are used in combination for HIV treatment and pre-exposure prophylaxis (PrEP). TFV disoproxil fumarate is a prodrug that undergoes diester hydrolysis to TFV. FTC and TFV are nucleoside/nucleotide reverse transcriptase inhibitors that upon p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:AIDS Res Hum Retroviruses
Prif Awduron: Figueroa, Dominique B., Madeen, Erin P., Tillotson, Joseph, Richardson, Paul, Cottle, Leslie, McCauley, Marybeth, Landovitz, Raphael J., Andrade, Adriana, Hendrix, Craig W., Mayer, Kenneth H., Wilkin, Timothy, Gulick, Roy M., Bumpus, Namandjé N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2018
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934973/
https://ncbi.nlm.nih.gov/pubmed/29455571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2017.0243
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