Cytochrome P450 Family 1 Inhibitors and Structure-Activity Relationships

Por Liu, Jiawang, Sridhar, Jayalakshmi, Foroozesh, Maryam
Publicado em 2013

A review of ceramide analogs as potential anticancer agents

Por Liu, Jiawang, Beckman, Barbara S., Foroozesh, Maryam
Publicado no Future Med Chem (2013)

Insights on Cytochrome P450 Enzymes and Inhibitors Obtained Through QSAR Studies

Por Sridhar, Jayalakshmi, Liu, Jiawang, Foroozesh, Maryam, Klein Stevens, Cheryl L.
Publicado em 2012

Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1)

Por Schroeder, Richard L, Tram, Phan, Liu, Jiawang, Foroozesh, Maryam, Sridhar, Jayalakshmi
Publicado no Expert Opin Ther Pat (2015)

In Silico Studies of Polyaromatic Hydrocarbon Inhibitors of Cytochrome P450 Enzymes 1A1, 1A2, 2A6, and 2B1

Por Sridhar, Jayalakshmi, Jin, Ping, Liu, Jiawang, Foroozesh, Maryam, Klein Stevens, Cheryl L.
Publicado em 2010

Development of Flavone Propargyl Ethers as Potent and Selective Inhibitors of Cytochrome P450 Enzymes 1A1 and 1A2

Por Sridhar, Jayalakshmi, Ellis, Jamie, Dupart, Patrick, Liu, Jiawang, Stevens, Cheryl L., Foroozesh, Maryam
Publicado em 2012

DESIGN, SYNTHESIS, AND EVALUATION OF CARBAZOLE ANALOGS AS POTENTIAL CYTOCHROME P450 INHIBITORS

Por Foroozesh, Maryam, Jiang, Quan, Sridhar, Jayalakshmi, Liu, Jiawang, Dotson, Brandan, McClain, Erika
Publicado no J Undergrad Chem Res (2013)

DESIGN, SYNTHESIS, AND EVALUATION OF A FAMILY OF PROPARGYL PYRIDINYL ETHERS AS POTENTIAL CYTOCHROME P450 INHIBITORS

Por Foroozesh, Maryam, Jiang, Quan, Sridhar, Jayalakshmi, Liu, Jiawang, Minaruzzaman, Dotson, Brandan, McClain, Erika
Publicado no J Undergrad Chem Res (2013)

Differential Inhibition of Cytochromes P450 3A4 and 3A5 by the Newly Synthesized Coumarin Derivatives 7-Coumarin Propargyl Ether and 7-(4-Trifluoromethyl)coumarin Propargyl Ether

Por Sridar, Chitra, Kent, Ute M., Noon, Kate, McCall, Alecia, Alworth, Bill, Foroozesh, Maryam, Hollenberg, Paul F.
Publicado em 2008

Ethynyl and Propynylpyrene Inhibitors of Cytochrome P450

Por Zhu, Naijue, Lightsey, Danielle, Liu, Jiawang, Foroozesh, Maryam, Morgan, Kathleen M., Stevens, Edwin D., Klein Stevens, Cheryl L.
Publicado em 2010

7-Ethynylcoumarins: Selective Inhibitors of Human Cytochrome P450s 1A1 and 1A2

Por Liu, Jiawang, Nguyen, Thong T., Dupart, Patrick S., Sridhar, Jayalakshmi, Zhang, Xiaoyi, Zhu, Naijue, Stevens, Cheryl L. Klein, Foroozesh, Maryam
Publicado em 2012

Reverse Type I Binding Spectra of Human Cytochrome P450 1B1 Induced by Flavonoid, Stilbene, Pyrene, Naphthalene, Phenanthrene, and Biphenyl Derivatives That Inhibit Catalytic Activ...

Por Shimada, Tsutomu, Tanaka, Katsuhiro, Takenaka, Shigeo, Foroozesh, Maryam K., Murayama, Norie, Yamazaki, Hiroshi, Guengerich, F. Peter, Komori, Masayuki
Publicado em 2009

Structure-Function Relationships of Inhibition of Human Cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 Flavonoid Derivatives

Por Shimada, Tsutomu, Tanaka, Katsuhiro, Takenaka, Shigeo, Murayama, Norie, Martin, Martha V., Foroozesh, Maryam K., Yamazaki, Hiroshi, Guengerich, F. Peter, Komori, Masayuki
Publicado em 2010

Pyranoflavones: A Group of Small-molecule Probes for Exploring the Active Site Cavities of Cytochrome P450 Enzymes 1A1, 1A2, and 1B1

Por Liu, Jiawang, Taylor, Shannon F., Dupart, Patrick S., Arnold, Corey L., Sridhar, Jayalakshmi, Jiang, Quan, Wang, Yuji, Skripnikova, Elena V., Zhao, Ming, Foroozesh, Maryam
Publicado em 2013

Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6

Por Shimada, Tsutomu, Takenaka, Shigeo, Kakimoto, Kensaku, Murayama, Norie, Lim, Young-Ran, Kim, Donghak, Foroozesh, Maryam K., Yamazaki, Hiroshi, Guengerich, F. Peter, Komori, Masayuki
Publicado no Chem Res Toxicol (2016)

Potent Mechanism-Based Inactivation Of Cytochrome P450 2B4 By 9-Ethynylphenanthrene: Implications For Allosteric Modulation Of Cytochrome P450 Catalysis()

Por Zhang, Haoming, Gay, Sean C., Shah, Manish, Foroozesh, Maryam, Liu, Jiawang, Osawa, Yoichi, Zhang, Qinghai, Stout, C. David, Halpert, James R., Hollenberg, Paul F.
Publicado em 2013

Interaction of Polycyclic Aromatic Hydrocarbons with Human Cytochrome P450 1B1 in Inhibiting Catalytic Activity

Por Shimada, Tsutomu, Murayama, Norie, Tanaka, Katsuhiro, Takenaka, Shigeo, Imai, Yoshio, Hopkins, Nancy E., Foroozesh, Maryam K., Alworth, Willam L., Yamazaki, Hiroshi, Guengerich, F. Peter, Komori, Masayuki
Publicado em 2008

Binding of Diverse Environmental Chemicals with Human Cytochromes P450 2A13, 2A6, and 1B1 and Enzyme Inhibition

Por Shimada, Tsutomu, Kim, Donghak, Murayama, Norie, Tanaka, Katsuhiro, Takenaka, Shigeo, Nagy, Leslie D., Folkman, Lindsay M., Foroozesh, Maryam K., Komori, Masayuki, Yamazaki, Hiroshi, Guengerich, F. Peter
Publicado em 2013

Oxidation of pyrene, 1-hydroxypyrene, 1-nitropyrene, and 1-acetylpyrene by human cytochrome P450 2A13

Por Shimada, Tsutomu, Takenaka, Shigeo, Murayama, Norie, Kramlinger, Valerie M., Kim, Joo-Hwan, Kim, Donghak, Liu, Jiawang, Foroozesh, Maryam K., Yamazaki, Hiroshi, Guengerich, F. Peter, Komori, Masayuki
Publicado no Xenobiotica (2015)

Ethynylflavones, Highly Potent, and Selective Inhibitors of Cytochrome P450 1A1

Por Goyal, Navneet, Liu, Jiawang, Lovings, La’Nese, Dupart, Patrick, Taylor, Shannon, Bellow, Sydni, Mensah, Lydia, McClain, Erika, Dotson, Brandan, Sridhar, Jayalakshmi, Zhang, Xiaoyi, Zhao, Ming, Foroozesh, Maryam
Publicado em 2014