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Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6

Naphthalene, phenanthrene, and biphenyl and their derivatives having different ethynyl, propynyl, butynyl, and propargyl ether substitutions were examined for their interaction with and oxidation by cytochromes P450 (P450) 2A13 and 2A6. Spectral interaction studies suggested that most of these chemi...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Shimada, Tsutomu, Takenaka, Shigeo, Kakimoto, Kensaku, Murayama, Norie, Lim, Young-Ran, Kim, Donghak, Foroozesh, Maryam K., Yamazaki, Hiroshi, Guengerich, F. Peter, Komori, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293596/
https://ncbi.nlm.nih.gov/pubmed/27137136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00083
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