Cytochrome P450 2A6 and Other Human P450 Enzymes in the Oxidation of Flavone and Flavanone

1. We previously reported that flavone and flavanone interact spectrally with cytochrome P450 (P450 or CYP) 2A6 and 2A13 and other human P450s and inhibit catalytic activities of these P450 enzymes. In this study, we studied abilities of CYP1A1, 1A2, 1B1, 2A6, 2A13, 2C9, and 3A4 to oxidize flavone a...

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Gepubliceerd in:Xenobiotica
Hoofdauteurs: Kakimoto, Kensaku, Murayama, Norie, Takenaka, Shigeo, Nagayoshi, Haruna, Lim, Young-Ran, Kim, Vitchan, Kim, Donghak, Yamazaki, Hiroshi, Komori, Masayuki, Guengerich, F. Peter, Shimada, Tsutomu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430112/
https://ncbi.nlm.nih.gov/pubmed/29310511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498254.2018.1426133
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