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Oxidation of Acenaphthene and Acenaphthylene by Human Cytochrome P450 Enzymes
Acenaphthene and acenaphthylene, two known environmental polycyclic aromatic hydrocarbon (PAH) pollutants, were incubated at 50 µM concentrations in a standard reaction mixture with human P450s 2A6, 2A13, 1B1, 1A2, 2C9, and 3A4 and the oxidation products were determined using HPLC and LC-MS. HPLC an...
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| Publicado en: | Chem Res Toxicol |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755721/ https://ncbi.nlm.nih.gov/pubmed/25642975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500505y |
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