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Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6

Naphthalene, phenanthrene, and biphenyl and their derivatives having different ethynyl, propynyl, butynyl, and propargyl ether substitutions were examined for their interaction with and oxidation by cytochromes P450 (P450) 2A13 and 2A6. Spectral interaction studies suggested that most of these chemi...

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Publicat a:Chem Res Toxicol
Autors principals: Shimada, Tsutomu, Takenaka, Shigeo, Kakimoto, Kensaku, Murayama, Norie, Lim, Young-Ran, Kim, Donghak, Foroozesh, Maryam K., Yamazaki, Hiroshi, Guengerich, F. Peter, Komori, Masayuki
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293596/
https://ncbi.nlm.nih.gov/pubmed/27137136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00083
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