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A review of ceramide analogs as potential anticancer agents

Ceramide serves as a central mediator in sphingolipid metabolism and signaling pathways, regulating many fundamental cellular responses. It is referred to as a “tumor suppressor lipid”, since it powerfully potentiates signaling events which drive apoptosis, cell cycle arrest, and autophagic response...

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Veröffentlicht in:Future Med Chem
Hauptverfasser: Liu, Jiawang, Beckman, Barbara S., Foroozesh, Maryam
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216473/
https://ncbi.nlm.nih.gov/pubmed/23919551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.107
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