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A review of ceramide analogs as potential anticancer agents
Ceramide serves as a central mediator in sphingolipid metabolism and signaling pathways, regulating many fundamental cellular responses. It is referred to as a “tumor suppressor lipid”, since it powerfully potentiates signaling events which drive apoptosis, cell cycle arrest, and autophagic response...
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| Veröffentlicht in: | Future Med Chem |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4216473/ https://ncbi.nlm.nih.gov/pubmed/23919551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.107 |
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