Interaction of Polycyclic Aromatic Hydrocarbons with Human Cytochrome P450 1B1 in Inhibiting Catalytic Activity

Eleven polycyclic aromatic hydrocarbons (PAHs) and 14 acetylenic PAHs and biphenyls were used to analyze interactions with cytochrome P450 (P450) 1B1 in inhibiting catalytic activity, using 7-ethoxyresorufin O-deethylation (EROD) as a model reaction. Most of the chemicals examined were direct inhibi...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shimada, Tsutomu, Murayama, Norie, Tanaka, Katsuhiro, Takenaka, Shigeo, Imai, Yoshio, Hopkins, Nancy E., Foroozesh, Maryam K., Alworth, Willam L., Yamazaki, Hiroshi, Guengerich, F. Peter, Komori, Masayuki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772130/
https://ncbi.nlm.nih.gov/pubmed/19548353
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