Effects of oligonucleotide length, mismatches and mRNA levels on C-5 propyne-modified antisense potency.

Por Flanagan, W M, Kothavale, A, Wagner, R W
Publicado em 1996

Persistence of seed-based activity following segmentation of a microRNA guide strand

Por Chorn, Guillaume, Zhao, Lihong, Sachs, Alan B., Flanagan, W. Michael, Lim, Lee P.
Publicado em 2010

Adenosine Modification May Be Preferred for Reducing siRNA Immune Stimulation

Por Fucini, Raymond V., Haringsma, Henry J., Deng, Patricia, Flanagan, W. Michael, Willingham, Aarron T.
Publicado em 2012

Analysis of the herpes simplex virus type 1 promoter controlling the expression of UL38, a true late gene involved in capsid assembly.

Por Flanagan, W M, Papavassiliou, A G, Rice, M, Hecht, L B, Silverstein, S, Wagner, E K
Publicado em 1991

p27(kip1) acts as a downstream effector of and is coexpressed with the β(1C) integrin in prostatic adenocarcinoma

Por Fornaro, Mara, Tallini, Giovanni, Zheng, Duo-Qi, Flanagan, W. Michael, Manzotti, Michela, Languino, Lucia R.
Publicado em 1999

Down-regulation of p21(WAF1/CIP1) or p27(Kip1) abrogates antiestrogen-mediated cell cycle arrest in human breast cancer cells

Por Cariou, Sandrine, Donovan, Jeffrey C. H., Flanagan, W. M., Milic, Andrea, Bhattacharya, Nandita, Slingerland, Joyce M.
Publicado em 2000

mRNA knockdown by single strand RNA is improved by chemical modifications

Por Haringsma, Henry J., Li, Jenny J., Soriano, Ferdie, Kenski, Denise M., Flanagan, W. Michael, Willingham, Aarron T.
Publicado em 2012

Using the Cancer Risk Management Model to evaluate colorectal cancer screening options for Canada

Por Coldman, A.J., Phillips, N., Brisson, J., Flanagan, W., Wolfson, M., Nadeau, C., Fitzgerald, N., Miller, A.B.
Publicado no Curr Oncol (2015)

Implementing low-dose computed tomography screening for lung cancer in Canada: implications of alternative at-risk populations, screening frequency, and duration

Por Evans, W.K., Flanagan, W.M., Miller, A.B., Goffin, J.R., Memon, S., Fitzgerald, N., Wolfson, M.C.
Publicado no Curr Oncol (2016)

A cytosine analog that confers enhanced potency to antisense oligonucleotides

Por Flanagan, W. Michael, Wolf, John J., Olson, Peter, Grant, Debbie, Lin, Kuei-Ying, Wagner, Richard W., Matteucci, Mark D.
Publicado em 1999

Physical characterization of the herpes simplex virus latency-associated transcript in neurons.

Por Wagner, E K, Devi-Rao, G, Feldman, L T, Dobson, A T, Zhang, Y F, Flanagan, W M, Stevens, J G
Publicado em 1988

First do no harm: extending the debate on the provision of preventive tamoxifen

Por Will, B P, Nobrega, K M, Berthelot, J-M, Flanagan, W, Wolfson, M C, Logan, D M, Evans, W K
Publicado em 2001

Single-stranded microRNA mimics

Por Chorn, Guillaume, Klein-McDowell, Molly, Zhao, Lihong, Saunders, Matthew A., Flanagan, W. Michael, Willingham, Aarron T., Lim, Lee P.
Publicado em 2012

Identification of the latency-associated transcript promoter by expression of rabbit beta-globin mRNA in mouse sensory nerve ganglia latently infected with a recombinant herpes sim...

Por Dobson, A T, Sederati, F, Devi-Rao, G, Flanagan, W M, Farrell, M J, Stevens, J G, Wagner, E K, Feldman, L T
Publicado em 1989

The herpes simplex virus latency-associated transcript is spliced during the latent phase of infection.

Por Wagner, E K, Flanagan, W M, Devi-Rao, G, Zhang, Y F, Hill, J M, Anderson, K P, Stevens, J G
Publicado em 1988

Nucleobase and Ribose Modifications Control Immunostimulation by a MicroRNA-122-mimetic RNA

Por Peacock, Hayden, Fucini, Raymond V., Jayalath, Prasanna, Ibarra-Soza, José M., Haringsma, Henry J., Flanagan, W. Michael, Willingham, Aarron, Beal, Peter A.
Publicado em 2011

siRNA-optimized Modifications for Enhanced In Vivo Activity

Por Kenski, Denise M, Butora, Gabor, Willingham, Aarron T, Cooper, Abby J, Fu, Wenlang, Qi, Ning, Soriano, Ferdie, Davies, Ian W, Flanagan, W Michael
Publicado em 2012

A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA.

Por Lewis, J G, Lin, K Y, Kothavale, A, Flanagan, W M, Matteucci, M D, DePrince, R B, Mook, R A, Hendren, R W, Wagner, R W
Publicado em 1996

Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing

Por Tep, Samnang, Mihaila, Radu, Freeman, Alexander, Pickering, Victoria, Huynh, Felicia, Tadin-Strapps, Marija, Stracks, Allison, Hubbard, Brian, Caldwell, Jeremy, Flanagan, W. Michael, Kuklin, Nelly A., Ason, Brandon
Publicado em 2012

Using the Cancer Risk Management Model to evaluate the health and economic impacts of cytology compared with human papillomavirus DNA testing for primary cervical cancer screening...

Por Popadiuk, C., Gauvreau, C.L., Bhavsar, M., Nadeau, C., Asakawa, K., Flanagan, W.M., Wolfson, M.C., Coldman, A.J., Memon, S., Fitzgerald, N., Lacombe, J., Miller, A.B.
Publicado no Curr Oncol (2016)