Eukaryotic Translation Initiation Factors 4G and 4A from Saccharomyces cerevisiae Interact Physically and Functionally

Por Neff, Carrie L., Sachs, Alan B.
Publicado em 1999

Poly(A) Tail Length Control in Saccharomyces cerevisiae Occurs by Message-Specific Deadenylation

Por Brown, Christine E., Sachs, Alan B.
Publicado em 1998

RNA Recognition Motif 2 of Yeast Pab1p Is Required for Its Functional Interaction with Eukaryotic Translation Initiation Factor 4G

Por Kessler, Steven H., Sachs, Alan B.
Publicado em 1998

Glucose Depletion Rapidly Inhibits Translation Initiation in Yeast

Por Ashe, Mark P., De Long, Susan K., Sachs, Alan B.
Publicado em 2000

Capped mRNA Degradation Intermediates Accumulate in the Yeast spb8-2 Mutant

Por Boeck, Ronald, Lapeyre, Bruno, Brown, Christine E., Sachs, Alan B.
Publicado em 1998

Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation

Por Tarun, Salvador Z., Wells, Sandra E., Deardorff, Julie A., Sachs, Alan B.
Publicado em 1997

Persistence of seed-based activity following segmentation of a microRNA guide strand

Por Chorn, Guillaume, Zhao, Lihong, Sachs, Alan B., Flanagan, W. Michael, Lim, Lee P.
Publicado em 2010

A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols

Por Ashe, Mark P., Slaven, John W., De Long, Susan K., Ibrahimo, Sálma, Sachs, Alan B.
Publicado em 2001

One-step affinity purification of the yeast ribosome and its associated proteins and mRNAs.

Por Inada, Toshifumi, Winstall, Eric, Tarun, Salvador Z, Yates, John R, Schieltz, Dave, Sachs, Alan B
Publicado em 2002

Mechanistically Probing Lipid-siRNA Nanoparticle-associated Toxicities Identifies Jak Inhibitors Effective in Mitigating Multifaceted Toxic Responses

Por Tao, Weikang, Mao, Xianzhi, Davide, Joseph P, Ng, Bruce, Cai, Mingmei, Burke, Paul A, Sachs, Alan B, Sepp-Lorenzino, Laura
Publicado em 2011

MicroRNA-like off-target transcript regulation by siRNAs is species specific

Por Burchard, Julja, Jackson, Aimee L., Malkov, Vladislav, Needham, Rachel H.V., Tan, Yejun, Bartz, Steven R., Dai, Hongyue, Sachs, Alan B., Linsley, Peter S.
Publicado em 2009

Biodistribution of Small Interfering RNA at the Organ and Cellular Levels after Lipid Nanoparticle-mediated Delivery

Por Shi, Bin, Keough, Ed, Matter, Andrea, Leander, Karen, Young, Stephanie, Carlini, Ed, Sachs, Alan B., Tao, Weikang, Abrams, Marc, Howell, Bonnie, Sepp-Lorenzino, Laura
Publicado em 2011

ApoB siRNA-induced Liver Steatosis is Resistant to Clearance by the Loss of Fatty Acid Transport Protein 5 (Fatp5)

Por Ason, Brandon, Castro-Perez, Jose, Tep, Samnang, Stefanni, Alice, Tadin-Strapps, Marija, Roddy, Thomas, Hankemeier, Thomas, Hubbard, Brian, Sachs, Alan B., Michael Flanagan, W., Kuklin, Nelly A., Mitnaul, Lyndon J.
Publicado em 2011

Development and characterization of a reconstituted yeast translation initiation system.

Por Algire, Mikkel A, Maag, David, Savio, Peter, Acker, Michael G, Tarun, Salvador Z, Sachs, Alan B, Asano, Katsura, Nielsen, Klaus H, Olsen, Deanne S, Phan, Lon, Hinnebusch, Alan G, Lorsch, Jon R
Publicado em 2002

Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5′-terminal phosphorylation both in vitro and in vivo

Por Kenski, Denise M., Cooper, Abby J., Li, Jenny J., Willingham, Aarron T., Haringsma, Henry J., Young, Tracy A., Kuklin, Nelly A., Jones, Jeffrey J., Cancilla, Mark T., McMasters, Daniel R., Mathur, Melina, Sachs, Alan B., Flanagan, W. Michael
Publicado em 2010

Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment

Por Abrams, Marc T, Koser, Martin L, Seitzer, Jessica, Williams, Stephanie C, DiPietro, Martha A, Wang, Weimin, Shaw, Andrew W, Mao, Xianzhi, Jadhav, Vasant, Davide, Joseph P, Burke, Paul A, Sachs, Alan B, Stirdivant, Steven M, Sepp-Lorenzino, Laura
Publicado em 2009

Quantitative evaluation of siRNA delivery in vivo

Por Pei, Yi, Hancock, Paula J., Zhang, Hangchun, Bartz, René, Cherrin, Craig, Innocent, Nathalie, Pomerantz, Colin J., Seitzer, Jessica, Koser, Martin L., Abrams, Marc T., Xu, Yan, Kuklin, Nelly A., Burke, Paul A., Sachs, Alan B., Sepp-Lorenzino, Laura, Barnett, Stanley F.
Publicado em 2010

Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9

Por Ason, Brandon, Tep, Samnang, Davis, Harry R., Xu, Yiming, Tetzloff, Glen, Galinski, Beverly, Soriano, Ferdie, Dubinina, Natalya, Zhu, Lei, Stefanni, Alice, Wong, Kenny K., Tadin-Strapps, Marija, Bartz, Steven R., Hubbard, Brian, Ranalletta, Mollie, Sachs, Alan B., Flanagan, W. Michael, Strack, Alison, Kuklin, Nelly A.
Publicado em 2011

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

Por Majercak, John, Ray, William J., Espeseth, Amy, Simon, Adam, Shi, Xiao-Ping, Wolffe, Carrie, Getty, Krista, Marine, Shane, Stec, Erica, Ferrer, Marc, Strulovici, Berta, Bartz, Steven, Gates, Adam, Xu, Min, Huang, Qian, Ma, Lei, Shughrue, Paul, Burchard, Julja, Colussi, Dennis, Pietrak, Beth, Kahana, Jason, Beher, Dirk, Rosahl, Thomas, Shearman, Mark, Hazuda, Daria, Sachs, Alan B., Koblan, Kenneth S., Seabrook, Guy R., Stone, David J.
Publicado em 2006

siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids

Por Tadin-Strapps, Marija, Peterson, Laurence B., Cumiskey, Anne-Marie, Rosa, Raymond L., Mendoza, Vivienne Halili, Castro-Perez, Jose, Puig, Oscar, Zhang, Liwen, Strapps, Walter R., Yendluri, Satyasri, Andrews, Lori, Pickering, Victoria, Rice, Julie, Luo, Lily, Chen, Zhu, Tep, Samnang, Ason, Brandon, Somers, Elizabeth Polizzi, Sachs, Alan B., Bartz, Steven R., Tian, Jenny, Chin, Jayne, Hubbard, Brian K., Wong, Kenny K., Mitnaul, Lyndon J.
Publicado em 2011