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Poly(A) Tail Length Control in Saccharomyces cerevisiae Occurs by Message-Specific Deadenylation

We report that newly synthesized mRNA poly(A) tails are matured to precise lengths by the Pab1p-dependent poly(A) nuclease (PAN) of Saccharomyces cerevisiae. These results provide evidence for an initial phase of mRNA deadenylation that is required for poly(A) tail length control. In RNA 3′-end proc...

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Main Authors: Brown, Christine E., Sachs, Alan B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1998
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109240/
https://ncbi.nlm.nih.gov/pubmed/9774670
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