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Poly(A) Tail Length Control in Saccharomyces cerevisiae Occurs by Message-Specific Deadenylation

We report that newly synthesized mRNA poly(A) tails are matured to precise lengths by the Pab1p-dependent poly(A) nuclease (PAN) of Saccharomyces cerevisiae. These results provide evidence for an initial phase of mRNA deadenylation that is required for poly(A) tail length control. In RNA 3′-end proc...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Brown, Christine E., Sachs, Alan B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109240/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774670/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6548
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