Adenosine Modification May Be Preferred for Reducing siRNA Immune Stimulation

Por Fucini, Raymond V., Haringsma, Henry J., Deng, Patricia, Flanagan, W. Michael, Willingham, Aarron T.
Publicado em 2012

mRNA knockdown by single strand RNA is improved by chemical modifications

Por Haringsma, Henry J., Li, Jenny J., Soriano, Ferdie, Kenski, Denise M., Flanagan, W. Michael, Willingham, Aarron T.
Publicado em 2012

Single-stranded microRNA mimics

Por Chorn, Guillaume, Klein-McDowell, Molly, Zhao, Lihong, Saunders, Matthew A., Flanagan, W. Michael, Willingham, Aarron T., Lim, Lee P.
Publicado em 2012

Nucleobase and Ribose Modifications Control Immunostimulation by a MicroRNA-122-mimetic RNA

Por Peacock, Hayden, Fucini, Raymond V., Jayalath, Prasanna, Ibarra-Soza, José M., Haringsma, Henry J., Flanagan, W. Michael, Willingham, Aarron, Beal, Peter A.
Publicado em 2011

siRNA-optimized Modifications for Enhanced In Vivo Activity

Por Kenski, Denise M, Butora, Gabor, Willingham, Aarron T, Cooper, Abby J, Fu, Wenlang, Qi, Ning, Soriano, Ferdie, Davies, Ian W, Flanagan, W Michael
Publicado em 2012

Post-transcriptional processing generates a diversity of 5′-modified long and short RNAs: Affymetrix/Cold Spring Harbor Laboratory ENCODE Transcriptome Project*

Por Fejes-Toth, Katalin, Sotirova, Vihra, Sachidanandam, Ravi, Assaf, Gordon, Hannon, Gregory J., Kapranov, Philipp, Foissac, Sylvain, Willingham, Aarron T., Duttagupta, Radha, Dumais, Erica, Gingeras, Thomas R.
Publicado em 2009

Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5′-terminal phosphorylation both in vitro and in vivo

Por Kenski, Denise M., Cooper, Abby J., Li, Jenny J., Willingham, Aarron T., Haringsma, Henry J., Young, Tracy A., Kuklin, Nelly A., Jones, Jeffrey J., Cancilla, Mark T., McMasters, Daniel R., Mathur, Melina, Sachs, Alan B., Flanagan, W. Michael
Publicado em 2010

The transcriptional diversity of 25 Drosophila cell lines

Por Cherbas, Lucy, Willingham, Aarron, Zhang, Dayu, Yang, Li, Zou, Yi, Eads, Brian D., Carlson, Joseph W., Landolin, Jane M., Kapranov, Philipp, Dumais, Jacqueline, Samsonova, Anastasia, Choi, Jeong-Hyeon, Roberts, Johnny, Davis, Carrie A., Tang, Haixu, van Baren, Marijke J., Ghosh, Srinka, Dobin, Alexander, Bell, Kim, Lin, Wei, Langton, Laura, Duff, Michael O., Tenney, Aaron E., Zaleski, Chris, Brent, Michael R., Hoskins, Roger A., Kaufman, Thomas C., Andrews, Justen, Graveley, Brenton R., Perrimon, Norbert, Celniker, Susan E., Gingeras, Thomas R., Cherbas, Peter
Publicado em 2011

The Developmental Transcriptome of Drosophila melanogaster

Por Graveley, Brenton R., Brooks, Angela N., Carlson, Joseph W., Duff, Michael O., Landolin, Jane M., Yang, Li, Artieri, Carlo G., van Baren, Marijke J., Boley, Nathan, Booth, Benjamin W., Brown, James B., Cherbas, Lucy, Davis, Carrie A., Dobin, Alex, Li, Renhua, Lin, Wei, Malone, John H., Mattiuzzo, Nicolas R., Miller, David, Sturgill, David, Tuch, Brian B., Zaleski, Chris, Zhang, Dayu, Blanchette, Marco, Dudoit, Sandrine, Eads, Brian, Green, Richard E., Hammonds, Ann, Jiang, Lichun, Kapranov, Phil, Langton, Laura, Perrimon, Norbert, Sandler, Jeremy E., Wan, Kenneth H., Willingham, Aarron, Zhang, Yu, Zou, Yi, Andrews, Justen, Bickel, Peter J., Brenner, Steven E., Brent, Michael R., Cherbas, Peter, Gingeras, Thomas R., Hoskins, Roger A., Kaufman, Thomas C., Oliver, Brian, Celniker, Susan E.
Publicado em 2010