Resistance-Resistant Antibiotics

Por Oldfield, Eric, Feng, Xinxin
Publicado no Trends Pharmacol Sci (2014)

Proteomics and SSH Analyses of ALA-Promoted Fruit Coloration and Evidence for the Involvement of a MADS-Box Gene, MdMADS1

Por Feng, Xinxin, An, Yuyan, Zheng, Jie, Sun, Miao, Wang, Liangju
Publicado no Front Plant Sci (2016)

ALA-Induced Flavonols Accumulation in Guard Cells Is Involved in Scavenging H(2)O(2) and Inhibiting Stomatal Closure in Arabidopsis Cotyledons

Por An, Yuyan, Feng, Xinxin, Liu, Longbo, Xiong, Lijun, Wang, Liangju
Publicado no Front Plant Sci (2016)

Chemical Exchange Saturation Transfer (CEST) Agents: Quantum Chemistry and MRI

Por Li, Jikun, Feng, Xinxin, Zhu, Wei, Oskolkov, Nikita, McMahon, Michael T., Oldfield, Eric
Publicado no Chemistry (2015)

Effect of Frankincense Extract on Nerve Recovery in the Rat Sciatic Nerve Damage Model

Por Jiang, Xiaowen, Ma, Jun, Wei, Qingwei, Feng, Xinxin, Qiao, Lu, Liu, Lin, Zhang, Binqing, Yu, Wenhui
Publicado no Evid Based Complement Alternat Med (2016)

Bacterial Cell Growth Inhibitors Targeting Undecaprenyl Diphosphate Synthase and Undecaprenyl Diphosphate Phosphatase

Por Wang, Yang, Desai, Janish, Zhang, Yonghui, Malwal, Satish R., Shin, Christopher J., Feng, Xinxin, Sun, Hong, Liu, Guizhi, Guo, Rey-Ting, Oldfield, Eric
Publicado no ChemMedChem (2016)

A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility, and Implications for Computer-Aided Drug Discovery

Por Kim, M. Olivia, Feng, Xinxin, Feixas, Ferran, Zhu, Wei, Lindert, Steffen, Bogue, Shannon, Sinko, William, de Oliveira, César, Rao, Guodong, Oldfield, Eric, McCammon, J. Andrew
Publicado no Chem Biol Drug Des (2014)

Reduction of Phosphorylated Synapsin I (Ser-553) Leads to Spatial Memory Impairment by Attenuating GABA Release after Microwave Exposure in Wistar Rats

Por Qiao, Simo, Peng, Ruiyun, Yan, Haitao, Gao, Yabing, Wang, Changzhen, Wang, Shuiming, Zou, Yong, Xu, Xinping, Zhao, Li, Dong, Ji, Su, Zhentao, Feng, Xinxin, Wang, Lifeng, Hu, Xiangjun
Publicado em 2014

Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity

Por No, Joo Hwan, de Macedo Dossin, Fernando, Zhang, Yonghui, Liu, Yi-Liang, Zhu, Wei, Feng, Xinxin, Yoo, Jinyoung Anny, Lee, Eunhae, Wang, Ke, Hui, Raymond, Freitas-Junior, Lucio H., Oldfield, Eric
Publicado em 2012

Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD(+), NADPH or NAD(+)/10-Oxogeranial: Reaction Mechanisms

Por Hu, Yumei, Liu, Weidong, Malwal, Satish R., Zheng, Yingying, Feng, Xinxin, Ko, Tzu-Ping, Chen, Chun-Chi, Xu, Zhongxia, Liu, Meixia, Han, Xu, Gao, Jian, Oldfield, Eric, Guo, Rey-Ting
Publicado no Angew Chem Int Ed Engl (2015)

Insights into the Mechanism of the Antibiotic-Synthesizing Enzyme MoeO5 from Crystal Structures of Different Complexes

Por Ren, Feifei, Ko, Tzu-Ping, Feng, Xinxin, Huang, Chun-Hsiang, Chan, Hsiu-Chien, Hu, Yumei, Wang, Ke, Ma, Yanhe, Liang, Po-Huang, Wang, Andrew H.-J., Oldfield, Eric, Guo, Rey-Ting
Publicado em 2012

Structure and Function of a “Head-to-Middle” Prenyltransferase: Lavandulyl Diphosphate Synthase

Por Liu, Meixia, Chen, Chun-Chi, Chen, Lu, Xiao, Xiansha, Zheng, Yingying, Huang, Jian-Wen, Liu, Weidong, Ko, Tzu-Ping, Cheng, Ya-Shan, Feng, Xinxin, Oldfield, Eric, Guo, Rey-Ting, Ma, Yanhe
Publicado no Angew Chem Int Ed Engl (2016)

Insights into TIM-barrel Prenyl Transferase Mechanisms: Crystal Structures of PcrB from Bacillus subtilis and Staphylococcus aureus

Por Ren, Feifei, Feng, Xinxin, Ko, Tzu-Ping, Huang, Chun-Hsiang, Hu, Yumei, Chan, Hsiu-Chien, Liu, Yi-Liang, Wang, Ke, Chen, Chun-Chi, Pang, Xuefei, He, Miao, Li, Yujie, Oldfield, Eric, Guo, Rey-Ting
Publicado em 2013

Structure, function and inhibition of ent-kaurene synthase from Bradyrhizobium japonicum

Por Liu, Wenting, Feng, Xinxin, Zheng, Yingying, Huang, Chun-Hsiang, Nakano, Chiaki, Hoshino, Tsutomu, Bogue, Shannon, Ko, Tzu-Ping, Chen, Chun-Chi, Cui, Yunfeng, Li, Jian, Wang, Iren, Hsu, Shang-Te Danny, Oldfield, Eric, Guo, Rey-Ting
Publicado em 2014

Crystal Structures of Ligand-Bound Octaprenyl Pyrophosphate Synthase from Escherichia coli Reveal the Catalytic and Chain-Length Determining Mechanisms()

Por Han, Xu, Chen, Chun-Chi, Kuo, Chih-Jung, Huang, Chun-Hsiang, Zheng, Yingying, Ko, Tzu-Ping, Zhu, Zhen, Feng, Xinxin, Wang, Ke, Oldfield, Eric, Wang, Andrew H.-J., Liang, Po-Huang, Guo, Rey-Ting, Ma, Yanhe
Publicado no Proteins (2014)

Structural and Functional Analysis of Bacillus subtilis YisP Reveal a Role of its Product in Biofilm Production

Por Feng, Xinxin, Hu, Yumei, Zheng, Yingying, Zhu, Wei, Li, Kai, Huang, Chun-Hsiang, Ko, Tzu-Ping, Ren, Feifei, Chan, Hsiu-Chien, Nega, Mulugeta, Bogue, Shannon, López, Daniel, Kolter, Roberto, Götz, Friedrich, Guo, Rey-Ting, Oldfield, Eric
Publicado no Chem Biol (2014)

Antiinfectives targeting enzymes and the proton motive force

Por Feng, Xinxin, Zhu, Wei, Schurig-Briccio, Lici A., Lindert, Steffen, Shoen, Carolyn, Hitchings, Reese, Li, Jikun, Wang, Yang, Baig, Noman, Zhou, Tianhui, Kim, Boo Kyung, Crick, Dean C., Cynamon, Michael, McCammon, J. Andrew, Gennis, Robert B., Oldfield, Eric
Publicado no Proc Natl Acad Sci U S A (2015)

Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyl Transferase MoeN5

Por Zhang, Lilan, Chen, Chun-Chi, Ko, Tzu-Ping, Huang, Jian-Wen, Zheng, Yingying, Liu, Weidong, Wang, Iren, Malwal, Satish R., Feng, Xinxin, Wang, Ke, Huang, Chun-Hsiang, Hsu, Shang-Te Danny, Wang, Andrew H.-J., Oldfield, Eric, Guo, Rey-Ting
Publicado no Angew Chem Int Ed Engl (2016)

Structure and Inhibition of Tuberculosinol Synthase and Decaprenyl Diphosphate Synthase from Mycobacterium tuberculosis

Por Chan, Hsiu-Chien, Feng, Xinxin, Ko, Tzu-Ping, Huang, Chun-Hsiang, Hu, Yumei, Zheng, Yingying, Bogue, Shannon, Nakano, Chiaki, Hoshino, Tsutomu, Zhang, Lilan, Lv, Pin, Liu, Wenting, Crick, Dean C., Liang, Po-Huang, Wang, Andrew H.-J., Oldfield, Eric, Guo, Rey-Ting
Publicado em 2014

Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases

Por Li, Kai, Schurig-Briccio, Lici A., Feng, Xinxin, Upadhyay, Ashutosh, Pujari, Venugopal, Lechartier, Benoit, Fontes, Fabio L., Yang, Hongliang, Rao, Guodong, Zhu, Wei, Gulati, Anmol, No, Joo Hwan, Cintra, Giovana, Bogue, Shannon, Liu, Yi-Liang, Molohon, Katie, Orlean, Peter, Mitchell, Douglas A., Freitas-Junior, Lucio, Ren, Feifei, Sun, Hong, Jiang, Tong, Li, Yujie, Guo, Rey-Ting, Cole, Stewart T., Gennis, Robert B., Crick, Dean C., Oldfield, Eric
Publicado em 2014